Effect of PEG and water-soluble chitosan coating on moxifloxacin-loaded PLGA long-circulating nanoparticles

@article{Mustafa2016EffectOP,
  title={Effect of PEG and water-soluble chitosan coating on moxifloxacin-loaded PLGA long-circulating nanoparticles},
  author={Sanaul Mustafa and V Kusum Devi and Roopa S Pai},
  journal={Drug Delivery and Translational Research},
  year={2016},
  volume={7},
  pages={27-36}
}
Moxifloxacin (MOX) is a Mycobacterium tuberculosis DNA gyrase inhibitor. Due to its intense hydrophilicity, MOX is cleared from the body within 24 h and required for repetitive doses which may then result in hepatotoxicity and acquisition of MOX resistant-TB, related with its use. To overcome the aforementioned limitations, the current study aimed to… CONTINUE READING