Effect of Oryza sativa extract on the progression of airway inflammation and remodeling in an experimental animal model of asthma.

@article{Lee2006EffectOO,
  title={Effect of Oryza sativa extract on the progression of airway inflammation and remodeling in an experimental animal model of asthma.},
  author={Seung-Ho Lee and Seul Min Choi and Young Sung Sohn and Kyung Koo Kang and Moohi Yoo},
  journal={Planta medica},
  year={2006},
  volume={72 5},
  pages={
          405-10
        }
}
Airway inflammation and remodeling in chronic asthma are characterized by airway eosinophilia, hyperplasia of smooth muscle and goblet cells, and subepithelial fibrosis. The present study was undertaken to evaluate the effects of DA-9201, an ethanolic extract of black rice (Oryza sativa L.), on airway inflammation and remodeling in a murine model of chronic asthma. BALB/c mice sensitized to ovalbumin (OVA) were chronically challenged with aerosolized OVA for 6 weeks. DA-9201 (30, 100, or 300 mg… 

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