Effect of Ocimum sanctum fixed oil on blood pressure, blood clotting time and pentobarbitone-induced sleeping time.

@article{Singh2001EffectOO,
  title={Effect of Ocimum sanctum fixed oil on blood pressure, blood clotting time and pentobarbitone-induced sleeping time.},
  author={S. Gyneshwar Singh and H M Rehan and Dipak Kanti Majumdar},
  journal={Journal of ethnopharmacology},
  year={2001},
  volume={78 2-3},
  pages={139-43}
}
Ocimum sanctum fixed oil produced hypotensive effect in anaesthetised dog, which seems to be due to its peripheral vasodilatory action. The oil increased blood-clotting time and percentage increase was comparable to aspirin and could be due to inhibition of platelet aggregation. The oil also increased pentobarbitone-induced sleeping time in rats indicating probable inhibitory effect of oil towards cytochromic enzyme responsible for hepatic metabolism of pentobarbitone. 
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