Effect of Nitrous Oxide Exposure During Surgery on the Homocysteine Concentrations of Children

@inproceedings{Pichardo2013EffectON,
  title={Effect of Nitrous Oxide Exposure During Surgery on the Homocysteine Concentrations of Children},
  author={Dubralicka Pichardo and Igor A Luginbuehl and Yaseer Abdul Shakur and Paul W. Wales and Ahmed El-Sohemy and Deborah L. O’Connor},
  year={2013}
}
In this study we determined the effect of nitrous oxide (N2O) on homocysteine concentrations in children and whether blood levels of folate, vitamin B12, B6, methylmalonic acid (MMA) and methylenetetrahydrofolate reductase C6777T genotype affected this relationship. Homocysteine was measured before and after N2O. Vitamin levels, MMA and genotype were determined preoperatively. Median age of the 32 participants was 11 months (3126 months). All children had folate and B6 levels above deficiency… CONTINUE READING

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