Effect of Nitric Oxide Pathway Regulation on Water/Sodium Balance and Renal Function in a Rodent Model of Acute Liver and Renal Failure

@article{Saracyn2014EffectON,
  title={Effect of Nitric Oxide Pathway Regulation on Water/Sodium Balance and Renal Function in a Rodent Model of Acute Liver and Renal Failure},
  author={M. Saracyn and T. Ząbkowski and R. Zdanowski and M. Brytan and J. Patera and Z. Nowak and G. Kade and Z. Wańkowicz},
  journal={Medical Science Monitor : International Medical Journal of Experimental and Clinical Research},
  year={2014},
  volume={20},
  pages={1735 - 1744}
}
Background The pathomechanism of acute hepatorenal syndrome (HRS), a particular form of acute renal failure that occurs in the course of acute liver injury, is still poorly understood. The aim of our study was to estimate the influence of the activation and inhibition of the nitric oxide pathway on the water/sodium balance and development of acute renal failure in the course of HRS. Material/Methods We used male Sprague-Dawley rats in the acute galactosamine (Ga1N) model of HRS. The nitric… Expand
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