Effect of NCB-02, atorvastatin and placebo on endothelial function, oxidative stress and inflammatory markers in patients with type 2 diabetes mellitus: a randomized, parallel-group, placebo-controlled, 8-week study.

@article{Usharani2008EffectON,
  title={Effect of NCB-02, atorvastatin and placebo on endothelial function, oxidative stress and inflammatory markers in patients with type 2 diabetes mellitus: a randomized, parallel-group, placebo-controlled, 8-week study.},
  author={Pingali Usharani and Ayesha Mateen and Madireddy Umamaheshwar Rao Naidu and Y. Satyanarayana Raju and Naval Chandra},
  journal={Drugs in R&D},
  year={2008},
  volume={9 4},
  pages={243-50}
}
BACKGROUND AND OBJECTIVE Hyperglycaemia leads to increased oxidative stress resulting in endothelial dysfunction. ACE inhibitors, antioxidants and HMG-CoA reductase inhibitors (statins) have been shown to improve endothelial function. The aim of this study was to compare the effects of NCB-02 (a standardized preparation of curcuminoids), atorvastatin and placebo on endothelial function and its biomarkers in patients with type 2 diabetes mellitus. METHODS A total of 72 patients with type 2… CONTINUE READING