Effect of NC100150 injection on the (1)H NMR linewidth of human whole blood ex vivo: dependency on blood oxygen tension.

@article{Bjrnerud2000EffectON,
  title={Effect of NC100150 injection on the (1)H NMR linewidth of human whole blood ex vivo: dependency on blood oxygen tension.},
  author={A. F. Bj\ornerud and Karen Briley-Saeb\o and Lars O Johansson and Kenneth E. Kellar},
  journal={Magnetic resonance in medicine},
  year={2000},
  volume={44 5},
  pages={803-7}
}
The linewidth of the (1)H NMR signal (7.05 T) of human whole blood titrated with a superparamagnetic contrast agent (NC100150 injection) was evaluated at different blood oxygen tensions. In deoxygenated blood and low contrast agent concentrations, NC100150 injection caused a decrease in linewidth. After reaching a minimum, the linewidth increased as the concentration of NC100150 injection increased. At the concentration corresponding to the minimum linewidth, the magnetization of the… CONTINUE READING