Effect of N-acetylcysteine for prevention of contrast nephropathy in patients with moderate to severe renal insufficiency: a randomized trial.

@article{Fung2004EffectON,
  title={Effect of N-acetylcysteine for prevention of contrast nephropathy in patients with moderate to severe renal insufficiency: a randomized trial.},
  author={Jeffrey Wing-Hong Fung and Cheuk Chun Szeto and Wilson W.M. Chan and Leo Chi-Chiu Kum and Anna K Y Chan and John Tai-hung Wong and Eugene B Wu and Gabriel Wai Kwok Yip and Joseph Yat-Sun Chan and Cheuk-Man Yu and Kam Sang Woo and John Elsby Sanderson},
  journal={American journal of kidney diseases : the official journal of the National Kidney Foundation},
  year={2004},
  volume={43 5},
  pages={
          801-8
        }
}
BACKGROUND The effect of N-acetylcysteine (NAC) to prevent contrast nephropathy (CN) in patients with moderate to severe renal insufficiency undergoing coronary angiography or interventions is not clear. METHODS This is a prospective, open-label, randomized, controlled trial. Ninety-one consecutive patients with a serum creatinine level of 1.69 to 4.52 mg/dL (149 to 400 micromol/L) undergoing coronary procedures were recruited and randomly assigned to administration of either oral NAC, 400 mg… CONTINUE READING
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