Effect of Mycobacterium butyricum on the hepatic cytochrome P-450 system of the mouse: influence of anti-inflammatory drug.

@article{Moreno1991EffectOM,
  title={Effect of Mycobacterium butyricum on the hepatic cytochrome P-450 system of the mouse: influence of anti-inflammatory drug.},
  author={J. J. Moreno and M C Castellote and J Queralt},
  journal={Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology},
  year={1991},
  volume={99 1-2},
  pages={
          7-10
        }
}
1. M. butyricum administration to rats induces arthritis and impairment in hepatic cytochrome P-450 activity. 2. This work was performed to verify if M. butyricum administrated to mice produces similar effects on cytochrome P-450 hepatic without involvement of articular lesions. 3. We also studied the role of arachidonate metabolites in the genesis and perpetuation of hepatic injury. 4. Intraperitoneal M. butyricum administration to mice increased sleeping time induced by pentobarbital and… CONTINUE READING