Effect of Mucuna pruriens on oxidative stress mediated damage in aged rat sperm.

@article{Suresh2010EffectOM,
  title={Effect of Mucuna pruriens on oxidative stress mediated damage in aged rat sperm.},
  author={S. Suresh and E. Prithiviraj and S. Prakash},
  journal={International journal of andrology},
  year={2010},
  volume={33 1},
  pages={
          22-32
        }
}
Mucuna pruriens Linn., a leguminous plant, has been recognized as an aphrodisiac and spermatogenic agent. Protective efficacy of M. pruriens on reactive oxygen species (ROS)-induced pathophysiological alterations in structural and functional integrity of epididymal sperm in aged Wister albino rat was analysed. Animals were grouped as groups I, II, III and IV, i.e. young (control), aged, aged treated with ethanolic extract (200 mg/kg b.w.) of M. pruriens and young rats treated with M. pruriens… Expand
Effect of Mucuna pruriens (Linn.) on mitochondrial dysfunction and DNA damage in epididymal sperm of streptozotocin induced diabetic rat.
TLDR
The present study has clearly demonstrated the potency of M. pruriens to reduce the diabetic induced sperm damage induced by oxidative stress (OS) and are encouraging to perform similar studies in human. Expand
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The ethanolic extract of M. pruriens seed significantly recovered or protected erectile tissue from the oxidative stress-induced degeneration by its antioxidant potentials and propound to serve mankind by the treatment of diabetes-induced erectile dysfunction. Expand
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TLDR
The results indicate a multi-factorial therapeutic activity in penile innervations towards sustaining the penile erection in the presence of the extract in aged rats and justifying the claim of traditional usage. Expand
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