Effect of Mucuna pruriens (Linn.) on sexual behavior and sperm parameters in streptozotocin-induced diabetic male rat.
@article{Suresh2012EffectOM, title={Effect of Mucuna pruriens (Linn.) on sexual behavior and sperm parameters in streptozotocin-induced diabetic male rat.}, author={Sekar Suresh and Seppan Prakash}, journal={The journal of sexual medicine}, year={2012}, volume={9 12}, pages={ 3066-78 } }
INTRODUCTION
Sexual dysfunction is one of the major secondary complications in the diabetic. Mucuna pruriens, a leguminous plant identified for its antidiabetic, aphrodisiac, and improving fertility properties, has been the choice of Indian traditional medicine.
AIM
Objective of the present study was to analyze the efficacy of M. pruriens on male sexual behavior and sperm parameters in long-term hyperglycemic male rats.
METHODS
Male albino rats were divided as group I control, group II…
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References
SHOWING 1-10 OF 51 REFERENCES
Dose- and time-dependent effects of ethanolic extract of Mucuna pruriens Linn. seed on sexual behaviour of normal male rats.
- Medicine, BiologyJournal of ethnopharmacology
- 2009
Adverse Effects of Rosemary (Rosmarinus officinalis L.) on Reproductive Function in Adult Male Rats
- BiologyExperimental biology and medicine
- 2007
Ingestion of rosemary by two groups of adult Sprague-Dawley rats at levels of 250 and 500 mg/kg body wt for 63 days was investigated for its effects on fertility, and markedly increased the number of fetal resorptions in female rats impregnated by group 2 males, thereby reducing their fertility.
Effect of Mucuna pruriens on oxidative stress mediated damage in aged rat sperm.
- Biology, MedicineInternational journal of andrology
- 2010
Sperm damage in ageing was significantly reduced by quenching ROS, improving antioxidant defence system and mitochondrial function, and present observation indicates the antioxidant enhancing property, free radical quenched ability and spermatogenic efficacy of the M. pruriens.
Traditional Indian anti-diabetic plants attenuate progression of renal damage in streptozotocin induced diabetic mice.
- Medicine, BiologyJournal of ethnopharmacology
- 2001
Aphrodisiac activity of Vanda tessellata (Roxb.) Hook. ex Don extract in male mice.
- Medicine
- 2000
The alcohol extract of V. tessellata flower stimulates the sexual behaviour of male mice and general toxicity, if any, in mice.
Testosterone replacement fails to reverse the adverse effects of streptozotocin-induced diabetes on sexual behavior in the male rat
- Biology, PsychologyPharmacology Biochemistry and Behavior
- 1990
Sustained hyperglycemia results in testicular dysfunction and reduced fertility potential in BBWOR diabetic rats.
- Medicine, BiologyThe American journal of physiology
- 1990
It is indicated that long-term diabetes with sustained hyperglycemia leads to significant testicular dysfunction associated with decreased fertility potential.
Changes in Mating Behavior, Erectile Function, and Nitric Oxide Levels in Penile Corpora Cavernosa in Streptozotocin-Diabetic Rats1
- Medicine, BiologyBiology of reproduction
- 2002
The results suggest that the diabetes-induced reduction in corporeal NO levels could be mainly due to the lack of some essential cofactors for NOS activity rather than to changes in the amount of enzyme proteins.
Gonadal dysfunction in the spontaneously diabetic BB rat.
- Medicine, BiologyMetabolism: clinical and experimental
- 1983
Association of hypogonadism and type II diabetes in men attending an outpatient erectile dysfunction clinic
- MedicineInternational Journal of Impotence Research
- 2006
The results show that hypogonadism is frequently associated with type II DM, at least in the 6th decade, and might exacerbate sexual dysfunction by reducing libido and mood and further compromising penile vascular reactivity.