Effect of Malignant Transformation and Arginine Limitation on Fibronectin and Other Cell Surface Macromolecules of Liver Epithelial Cultures 1

Abstract

Surface labeling of 'normal" nontumorigenic rat liver epithe lial cells permitted the detection of a 140,000-dalton species and of another 230,000-dalton molecule that comigrated with fibronectin, an external transformation-sensitive protein of fibroblasts. Reaction of surface-labeled normal liver epithelial cells with anti-fibronectin serum led to the… (More)

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