Effect of MK-801 and U83836E on a porcine brain capillary endothelial cell barrier during hypoxia.

Abstract

The present study investigated the influence of MK-801 (N-methyl-D-aspartate receptor antagonist) and U83836E (antioxidative aminosteroid) on the permeability of sodium fluorescein through a cell barrier during hypoxia (2 h 95% N2/5% CO2). The barrier consisted of porcine brain capillary endothelial cells and of cerebral rat astrocytes cultivated on two… (More)

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