Effect of Lactobacillus plantarum on diarrhea and intestinal barrier function of young piglets challenged with enterotoxigenic Escherichia coli K88.

@article{Yang2014EffectOL,
  title={Effect of Lactobacillus plantarum on diarrhea and intestinal barrier function of young piglets challenged with enterotoxigenic Escherichia coli K88.},
  author={K. M. Yang and Z. Y. Jiang and Chuntian Zheng and L. Wang and X. F. Yang},
  journal={Journal of animal science},
  year={2014},
  volume={92 4},
  pages={
          1496-503
        }
}
The present study was performed to investigate the preventative effect of Lactobacillus plantarum on diarrhea in relation to intestinal barrier function in young piglets challenged with enterotoxigenic Escherichia coli (ETEC) K88. Seventy-two male piglets (4 d old) were assigned to 2 diets (antibiotic-free basal diet with or without L. plantarum, 5 × 10(10) cfu/kg diet) and subsequently challenged or not with ETEC K88 (1 × 10(8) cfu per pig) on d 15 in a 2 × 2 factorial arrangement of… 
View on PubMed
animalsciencepublications.org
110 Citations
Highly Influential Citations
3
Background Citations
27
Methods Citations
2
Results Citations
6

110 Citations

Citation Type

Citation Type

Effects of Lactobacillus plantarum on the intestinal morphology, intestinal barrier function and microbiota composition of suckling piglets.
TLDR
Findings indicate that L. plantarum 299v facilitates the gut health of suckling piglets, probably by improving the intestinal morphology and intestinal barrier function and by modifying the structure of the gut microbiota.
Probiotic supplementation protects weaned pigs against enterotoxigenic Escherichia coli K88 challenge and improves performance similar to antibiotics.
TLDR
PB supplementation protected the pigs against ETEC K88 infection by enhancing immune responses and attenuating intestinal damage and improved the performance and nutrient digestibility of weaned pigs.
Effects of Lactobacillus acidophilus dietary supplementation on the performance, intestinal barrier function, rectal microflora and serum immune function in weaned piglets challenged with Escherichia coli lipopolysaccharide
TLDR
Results indicate that feeding with L. acidophilus improved growth performance and protected against LPS-induced inflammatory status.
Enterococcus faecium NCIMB 10415 administration improves the intestinal health and immunity in neonatal piglets infected by enterotoxigenic Escherichia coli K88
TLDR
It is suggested that oral administration of E. faecium alleviated the intestinal injury and diarrhea severity of neonatal piglets challenged by ETEC, partly through improving the intestinal microbiota and immune response.
Effects of Lactobacillus acidophilus and zinc oxide on the growth performance, jejunal morphology and immune function of weaned piglet following an Escherichia coli K88 challenge
TLDR
The administration of LA or ZnO was effective in improving growth performance of weaned piglets, and both supplementations may benefit the jejunal development and immune function of piglets following E. coli K88 challenge.
Dietary fermented soybean meal inclusion improves growth performance and ileal barrier function of the weaned piglets challenged by enterotoxigenic Escherichia coli K88
Evaluation of coated zinc oxide in young pigs challenged with enterotoxigenic Escherichia coli K88
Effects of Lactobacillus reuteri LR1 on the growth performance, intestinal morphology, and intestinal barrier function in weaned pigs.
TLDR
It is indicated that dietary LR1 supplementation at 5 × 1010 cfu/kg improved growth performance, intestinal morphology, and intestinal barrier function in weaned pigs.
Effects of an F18 enterotoxigenic Escherichia coli challenge on growth performance, immunological status, and gastrointestinal structure of weaned pigs and the potential protective effect of direct-fed microbial blends
TLDR
The impact of an ETEC challenge on intestinal function and the immune system has been revealed, information critical to developing improved treatment regimes is revealed.
Early supplementation with Lactobacillus plantarum in liquid diet modulates intestinal innate immunity through TLR4-mediated mitogen-activated protein kinase signaling pathways in young piglets challenged with Escherichia coli K88.
TLDR
LP supplementation in liquid diet possesses anti-inflammatory activity and modulates the intestinal innate immunity during the early life of young piglets challenged with ETEC K88, which might be attributed to suppression of TLR4-mediated mitogen-activated protein kinase (MAPK) signaling pathways.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 29 REFERENCES
Effect of Lactobacillus plantarum CJLP243 on the growth performance and cytokine response of weaning pigs challenged with enterotoxigenic Escherichia coli.
TLDR
Findings suggest that L. plantarum CJLP243, at a concentration of 10(10) cfu/kg, may serve as a potential alternative to antibiotic supplementation to improve the growth and health performance of weaning pigs, especially during acute inflammation of the gut after bacterial infections.
Chito-oligosaccharide reduces diarrhea incidence and attenuates the immune response of weaned pigs challenged with Escherichia coli K88.
TLDR
Chito-oligosaccharide, at the amount used in this experiment, does not seem to be an effective substitute for antibiotics as a growth promoter for newly weaned pigs challenged with E. coli.
Effects of lactobacillus plantarum ZJ316 on pig growth and pork quality
TLDR
The results showed that, the L. plantarum ZJ316 has probiotic effects on pig growth and that these effects are dose dependent, and the mechanisms underlying its action require further study.
Casein glycomacropeptide in the diet may reduce Escherichia coli attachment to the intestinal mucosa and increase the intestinal lactobacilli of early weaned piglets after an enterotoxigenic E. coli K88 challenge
TLDR
It is concluded that CGMP may improve gut health by diminishing the adhesion of ETEC K88 to the intestinal mucosa, by increasing the lactobacilli population in the intestine and by reducing the overgrowth of enterobacteria in the digestive tract of piglets after an ET EC K88 challenge.
Evaluation of Lactobacillus rhamnosus GG using an Escherichia coli K88 model of piglet diarrhoea: Effects on diarrhoea incidence, faecal microflora and immune responses.
The novel porcine Lactobacillus sobrius strain protects intestinal cells from enterotoxigenic Escherichia coli K88 infection and prevents membrane barrier damage.
TLDR
The data indicate that L. sobrius exerts protection against the harmful effects of ETEC by different mechanisms, including pathogen adhesion inhibition and maintenance of membrane barrier integrity through IL-10 regulation.
Response of early-weaned pigs to an enterotoxigenic Escherichia coli (K88) challenge when fed diets containing spray-dried porcine plasma or pea protein isolate plus egg yolk antibody, zinc oxide, fumaric acid, or antibiotic.
TLDR
SDPP, EYA, ZnO, FA, and AB may have provided passive control to ETEC (K88) infection and potentially enabled young pigs to efficiently utilize a PPI-based diet.
Protective effects of N-acetylcysteine on intestinal functions of piglets challenged with lipopolysaccharide
TLDR
Dietary NAC supplementation alleviates the mucosal damage and improves the absorptive function of the small intestine in LPS-challenged piglets, and prevented the L PS-induced decrease in claudin-1 and occludin expression in the jejunal and ileal mucosae.
Lactobacillus plantarum prevents the development of colitis in IL-10-deficient mouse by reducing the intestinal permeability
TLDR
This study showed that tight junction associated proteins were increased after the pre-treatment of L. plantarum, and may prevent the development of colitis in IL-10-deficient mice by blocking changes in the expression of TJ proteins, TJ structure and intestinal permeability.
Regulation of human epithelial tight junction proteins by Lactobacillus plantarum in vivo and protective effects on the epithelial barrier.
TLDR
The results identifying commensal bacterial stimulation of TLR2 in the gut epithelium as a regulator of epithelial integrity have important implications for understanding probiotic mechanisms and the control of intestinal homeostasis.
...
1
2
3
...