Effect of LPS administration on the expression of POMC, NPY, galanin, CART and MCH mRNAs in the rat hypothalamus.

@article{Sergeyev2001EffectOL,
  title={Effect of LPS administration on the expression of POMC, NPY, galanin, CART and MCH mRNAs in the rat hypothalamus.},
  author={Valeriy Sergeyev and Christian Broberger and Tomas G M H{\"o}kfelt},
  journal={Brain research. Molecular brain research},
  year={2001},
  volume={90 2},
  pages={93-100}
}
Anorexia and weight loss are manifestations of inflammation seen both in patients and in experimental animal models such as the lipopolysaccharide (LPS)-treated rat. Using in situ hybridization, the levels of mRNAs encoding proopiomelanocortin (POMC), neuropeptide Y (NPY), galanin, melanin-concentrating hormone (MCH) and cocaine- and amphetamine-regulated… CONTINUE READING