Effect of LFA-1 and ICAM-1 antibody treatment on murine corneal allograft survival.

  title={Effect of LFA-1 and ICAM-1 antibody treatment on murine corneal allograft survival.},
  author={Y G He and Jessamee Mellon and Ron Apte and Jerry Y. Niederkorn},
  journal={Investigative ophthalmology & visual science},
  volume={35 8},
PURPOSE To examine the effect of anti-LFA-1 and anti-ICAM-1 antibody treatment on orthotopic corneal graft survival in a mouse model. METHODS Anti-LFA-1 and anti-ICAM-1 antibodies were administered intraperitoneally before and shortly after orthotopic corneal transplantation. Grafts were observed by biomicroscopy, and survival times were determined. Cytotoxic T lymphocyte (CTL) and delayed-type hypersensitivity (DTH) responses to donor alloantigens were assessed at selected times after… CONTINUE READING

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Effect of anti LFA-1 (CDIIa) monoclonal antibodies in acute rejection in human kidney transplantation

BL Mauff, M Hourmant, J-P Rongier, M. Hira
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Monoclonal antibodies to ICAM-1 and LFA-1 prolong corneal allograft survival in a rat penetrating keratoplasty model. ARVO Abstracts

R Muramatsu, S Kumakura, N Shimizu, K Okumura, M. Miyasaka
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