Effect of LET on the yield and quality of chromosomal damage in metaphase cells: a time-course study.

@article{Ritter2002EffectOL,
  title={Effect of LET on the yield and quality of chromosomal damage in metaphase cells: a time-course study.},
  author={Sylvia Ritter and Elena Nasonova and E Gudowska-Novak},
  journal={International journal of radiation biology},
  year={2002},
  volume={78 3},
  pages={191-202}
}
PURPOSE To investigate further the effect of linear energy transfer (LET) on the yield and quality of aberrations at different post-irradiation sampling times. MATERIALS AND METHODS V79 G(1)-cells were exposed to either 10.6 MeV u-1 Ne ions (360 keV microm-1) or 11.1 MeV u-1 Kr ions (3980 keV microm-1) and chromosomal damage was measured in metaphase cells at several 2-h sampling intervals up to 30 h post-irradiation. To differentiate between cells in the first and second post-irradiation… CONTINUE READING

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