Effect of L-carnitine on myocardial metabolism: results of a balanced, placebo-controlled, double-blind study in patients undergoing open heart surgery.

@article{Pastoris1998EffectOL,
  title={Effect of L-carnitine on myocardial metabolism: results of a balanced, placebo-controlled, double-blind study in patients undergoing open heart surgery.},
  author={Ornella Pastoris and Maurizia Dossena and P. Foppa and Mariana Catapano and Eloisa Arbustini and Ornella Bellini and Barbara Dal Bello and Gaetano Minzioni and Piero Ceriana and Nicoletta Barzaghi},
  journal={Pharmacological research},
  year={1998},
  volume={37 2},
  pages={115-22}
}
The effects of L-carnitine on cardiac performance after open heart surgery were evaluated in a balanced, placebo-controlled, double-blind study in 38 patients. Preoperative haemodynamic status was good in all of them. Seventeen subjects underwent mitral valve replacement and 19 patients coronary artery bypass grafting. Five grams L-carnitine were given intravenously over 2 h, twice daily for 5 consecutive days; moreover, 10 g L-carnitine in 1500 ml cardioplegia were administered through the… CONTINUE READING