Effect of L‐carnitine on the synthesis of nitric oxide in RAW 264·7 murine macrophage cell line

@article{Ko2011EffectOL,
  title={Effect of L‐carnitine on the synthesis of nitric oxide in RAW 264·7 murine macrophage cell line},
  author={Aslı Koç and Tulin Ozkan and Arzu Zeynep Karabay and Asuman Sunguroglu and Fugen Aktan},
  journal={Cell Biochemistry and Function},
  year={2011},
  volume={29}
}
L‐Carnitine (β‐hydroxy‐γ‐trimethyl aminobutyric acid) plays a critical role in inflammatory diseases by modulating inflammatory cell functions. Inducible nitric oxide synthase (iNOS), a proinflammatory enzyme responsible for the generation of nitric oxide (NO), has been implicated in the pathogenesis of inflammatory diseases. Mechanism of action of L‐carnitine on inflammation via iNOS and nuclear factor κB (NF‐κB) is unclear. In this study, we aimed to investigate the effect of L‐carnitine on… 

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