Effect of K+ channels in the apical plasma membrane on epithelial secretion based on secondary active Cl− transport

@article{Cook1989EffectOK,
  title={Effect of K+ channels in the apical plasma membrane on epithelial secretion based on secondary active Cl− transport},
  author={David I. Cook and John Atherton Young},
  journal={The Journal of Membrane Biology},
  year={1989},
  volume={110},
  pages={139-146}
}
Models of epithelial salt secretion, involving secondary active transport of Cl− [9], locate the K+ conductance of the plasma membrane exclusively in the basolateral membrane, although there is considerable experimental evidence to show that many secretory epithelia do have a significant apical K+ conductance. We have used an equivalent circuit model to examine the effect of an apical K+ conductance on the composition and flow rate of the fluid secreted by an epithelium in which secretion is… CONTINUE READING

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Ionic dependence of exocytosis from permeabilized acini of the rat pancreas

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