Effect of Ionic Medium on Carbacholine-Induced Membrane Depolarization in Lumbricus Terrestris Somatic Muscle Cells

@article{Volkov2002EffectOI,
  title={Effect of Ionic Medium on Carbacholine-Induced Membrane Depolarization in Lumbricus Terrestris Somatic Muscle Cells},
  author={Eugeny M Volkov and Leniz F. Nurullin},
  journal={Bulletin of Experimental Biology and Medicine},
  year={2002},
  volume={134},
  pages={428-429}
}
Carbacholine depolarizes Lumbricus terrestris myocyte membrane. Addition of verapamil, tetrodotoxin, removal of K+, Cl-, and Ca2+, and replacement of Ca2+ with Mn2+ in the bathing solution did not prevent the carbacholine-induced decrease in resting potential, but in a sodium-free medium carbacholine was ineffective. It was hypothesized that depolarization… CONTINUE READING