Effect of Interesterification of Palmitic Acid-rich Triacylglycerol on Postprandial Lipid and Factor VII Response

@article{Berry2007EffectOI,
  title={Effect of Interesterification of Palmitic Acid-rich Triacylglycerol on Postprandial Lipid and Factor VII Response},
  author={S. Berry and R. Woodward and C. Yeoh and G. Miller and T. Sanders},
  journal={Lipids},
  year={2007},
  volume={42},
  pages={315-323}
}
The process of interesterification results in changes in triacylglycerol (TAG) structure and is used to increase the melting point of dietary fats. The acute health effects of this process on palmitic acid-rich fats are uncertain with regard to postprandial lipemia, insulin and factor VII activated (FVIIa) concentrations. Two randomized crossover trials in healthy male subjects compared the effects of meals containing 50 g fat [interesterified palm oil (IPO) versus native palm oil (NPO); n = 20… Expand
Palmitic acid in the sn-2 position of triacylglycerols acutely influences postprandial lipid metabolism.
TLDR
Fats with a higher proportion of palmitic acid in the sn-2 position decrease postprandial lipemia in healthy subjects, as measured by plasma concentrations of nonesterified fatty acid and triacylglycerol. Expand
Palmitic acid in the sn2 position of triacylglycerols acutely influences postprandial lipid metabolism 1 – 3
Background: The triacylglycerol structure of saturated fats may influence postprandial lipemia. Objective: We tested the hypothesis that high-fat meals rich in palmitic acid (16:0) in the sn-2Expand
An Interesterified Palm Olein Test Meal Decreases Early-Phase Postprandial Lipemia Compared to Palm Olein: a Randomized Controlled Trial
TLDR
Testing the hypothesis that high-fat meals rich in interesterified palm olein (IPO) decrease lipemia and alter plasma lipoprotein fraction composition compared to native palm Olein (NPO) in men aged 40–70 years with fasting TAG concentrations found it to be correct. Expand
Interesterified palm olein lowers postprandial glucose-dependent insulinotropic polypeptide response in type 2 diabetes
TLDR
This study shows no adverse effect of interesterification on hormones associated with glucose homeostasis notably GLP-1 in T2D subjects. Expand
Palmitic acid–rich oils with and without interesterification lower postprandial lipemia and increase atherogenic lipoproteins compared with a MUFA-rich oil: A randomized controlled trial
TLDR
Interesterification did not modify fat digestion, postprandial lipemia, or lipid metabolism measured by stable isotope and DGM analysis, and increased proatherogenic large triacylglycerol-rich lipoprotein remnant and small LDL particles following the SFA-rich fats relative to RO adds a new postpr andial dimension to the mechanistic evidence linking SFAs to cardiovascular disease risk. Expand
Effects of Lipid Structure Changed by Interesterification on Melting Property and Lipemia
TLDR
The confounding of two factors that are both changed by interesterization, TAG structure and solid fat content as the main limitation on understanding how interesterification affects lipemia is emphasized. Expand
Palmitic Acid Versus Stearic Acid: Effects of Interesterification and Intakes on Cardiometabolic Risk Markers—A Systematic Review
TLDR
Compared with palmitic acid, stearic acid lowers low-density lipoprotein (LDL)-cholesterol, which is a well-known risk factor for coronary heart disease (CHD), but its effects on other cardiometabolic risk markers have been studied less extensively. Expand
Effects of Plant Oil Interesterified Triacylglycerols on Lipemia and Human Health
TLDR
The role of TAG structures and interesterified palmitic and stearic acid-rich fats on fasting and postprandial lipemia is provided, focusing on their physical properties and their effects on human health. Expand
Triacylglycerol structure and interesterification of palmitic and stearic acid-rich fats: an overview and implications for cardiovascular disease
  • S. Berry
  • Medicine, Chemistry
  • Nutrition Research Reviews
  • 2009
TLDR
It is probable that differences in the physical characteristics of fats resulting from interesterification and changes in TAG structure are key determinants of the level of postprandial lipaemia, rather than the position of fatty acids in the TAG. Expand
Palmitic acid in the sn-2 position decreases glucose-dependent insulinotropic polypeptide secretion in healthy adults
TLDR
Dietary TAGs with an increased proportion of palmitic acid in the sn-2 position do not have acute adverse effects on the insulin and glucose response to meals in healthy men and women, but they decrease GIP release. Expand
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References

SHOWING 1-10 OF 32 REFERENCES
Influence of triacylglycerol structure on the postprandial response of factor VII to stearic acid-rich fats.
TLDR
Symmetrical stearic acid-rich triacylglycerol with oleic acid in the sn-2 position appears to be absorbed more rapidly than is asymmetrical triacyLglycerols with long-chain saturated fatty acids in thesn-2 positions, which leads to activation of FVII. Expand
Influence of a stearic acid-rich structured triacylglycerol on postprandial lipemia, factor VII concentrations, and fibrinolytic activity in healthy subjects.
TLDR
The consumption of stearic acid in the form of a structured triacylglycerol leads to less of an increase in plasma Triacyl glycerol and in FVII:c than does a meal enriched in cocoa butter or oleate. Expand
Effect on plasma lipids of interesterifying a mix of edible oils.
TLDR
This study shows that interesterification of oils used to harden margarines does not raise plasma cholesterol more than does the margarine's constituent fatty acids. Expand
Effects of palm oil and transesterified palm oil on chylomicron and VLDL triacylglycerol structures and postprandial lipid response.
TLDR
The relationship between TAG molecular structures in dietary fats and in lipoproteins provides new means for understanding the effects of fatty acid positional distribution on human lipid metabolism. Expand
Influence of fatty acid chain length and cis/trans isomerization on postprandial lipemia and factor VII in healthy subjects (postprandial lipids and factor VII).
TLDR
Results do not support the hypothesis that dietary stearate and elaidate are responsible for the postprandial increases in factor VII coagulant activity associated with high fat intakes. Expand
Effect of synthetic triglycerides of myristic, palmitic, and stearic acid on serum lipoprotein metabolism
TLDR
In contrast to studies involving natural fats, 14:0, fed as a synthetic triglyceride, was less cholesterolemic than 16:0 in a majority of subjects, and stearic acid was neutral compared to 14-0 and 16-0. Expand
Effect of individual dietary fatty acids on postprandial activation of blood coagulation factor VII and fibrinolysis in healthy young men.
TLDR
The results indicate a lesser increase in FVIIa after the consumption of saturated fats, especially the S fat, than after unsaturated test fats, and this increase was not significantly associated with the level of lipemia, plasma FFAs, or plasma lipoprotein lipase activity. Expand
Use of structured triacylglycerols containing predominantly stearic and oleic acids to probe early events in metabolic processing of dietary fat.
TLDR
The environment for lipoprotein lipase action in adipose tissue in vivo is likely to be highly organized, such that there is no release of monoacylglycerol, nor preferential uptake or release of fatty acids from chylomicron-triacyl glycerol according to the nature or the position within triacyl Glycerol of the fatty acid. Expand
Acute effects of dietary fat composition on postprandial plasma bile acid and cholecystokinin concentrations in healthy premenopausal women
TLDR
Testing the hypothesis that fatty acid chain length and degree of unsaturation differ with regard to their influence on the postprandial release of cholecystokinin (CCK) and the subsequent increase in plasma bile acid concentrations in eighteen healthy premenopausal women concluded that meals rich in linoleate are a potent stimulus for CCK release and lead to prolonged elevations of Plasma bile acids. Expand
Effects of fats high in stearic acid on lipid and lipoprotein concentrations in men.
The effects of beef tallow and cocoa butter, two fats with a high stearic acid content (C18:0), on serum lipid and lipoprotein concentrations were compared with the effects of butter fat and oliveExpand
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