Effect of Intensive Statin Therapy on Coronary High-Intensity Plaques Detected by Noncontrast T1-Weighted Imaging: The AQUAMARINE Pilot Study.

@article{Noguchi2015EffectOI,
  title={Effect of Intensive Statin Therapy on Coronary High-Intensity Plaques Detected by Noncontrast T1-Weighted Imaging: The AQUAMARINE Pilot Study.},
  author={Teruo Noguchi and Atsushi Tanaka and Tomohiro Kawasaki and Yoichi Goto and Yoshiaki Morita and Yasuhide Asaumi and Kazuhiro Nakao and Reiko Fujiwara and Kunihiro Nishimura and Yoshihiro Miyamoto and Masaharu Ishihara and Hisao Ogawa and Nobuhiko Koga and Jagat P Narula and Satoshi Yasuda},
  journal={Journal of the American College of Cardiology},
  year={2015},
  volume={66 3},
  pages={245-256}
}
BACKGROUND Coronary high-intensity plaques detected by noncontrast T1-weighted imaging may represent plaque instability. High-intensity plaques can be quantitatively assessed by a plaque-to-myocardium signal-intensity ratio (PMR). OBJECTIVES This pilot, hypothesis-generating study sought to investigate whether intensive statin therapy would lower PMR. METHODS Prospective serial noncontrast T1-weighted magnetic resonance imaging and computed tomography angiography were performed in 48… CONTINUE READING
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