Effect of Infection with M. Tuberculosis and of Tuberculin Shock on the Succinic Dehydrogenase Activity of Guinea Pig Tissues

The kidney of guinea pigs infected with the H37Rv and BCG strains of M. tuberculosis showed a diminution in succinic dehydrogenase activity when measured by the tetrazolium technique. This effect was also seen in the liver and spleen of animals infected with the BCG strain. Sensitized animals showed similar results when given tuberculin in sublethal doses… CONTINUE READING