Effect of IGF-I and TNF-α on intensification of steroid pathways in women with PCOS phenotypes are not identical. Enhancement of progesterone pathway in women with PCOS increases the concentration of TNF-α.

@article{Szczuko2016EffectOI,
  title={Effect of IGF-I and TNF-α on intensification of steroid pathways in women with PCOS phenotypes are not identical. Enhancement of progesterone pathway in women with PCOS increases the concentration of TNF-α.},
  author={Małgorzata Szczuko and Marta Zapałowska-Chwy{\'c} and Arleta Drozd and Dominika Maciejewska and Andrzej Starczewski and Ewa Stachowska},
  journal={Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology},
  year={2016},
  volume={32 9},
  pages={
          714-717
        }
}
OBJECTIVE The aim of this study was to determine the correlations between the concentration of tumor necrosis factor (TNF-α) and insulin-like growth factor I (IGF-I) in each woman with polycystic ovary syndrome (PCOS) phenotypes based on the levels of androgen. METHODS Two groups of women with PCOS differing in their levels of androgens. The test group composed of 39 women with PCOS according to the Rotterdam criteria in their reproductive age. The hormonal levels of luteinizing hormone (LH… CONTINUE READING