Effect of Histamine H2-Receptor Antagonists on Vitamin B12 Absorption

@article{Force1992EffectOH,
  title={Effect of Histamine H2-Receptor Antagonists on Vitamin B12 Absorption},
  author={R. Force and M. Nahata},
  journal={Annals of Pharmacotherapy},
  year={1992},
  volume={26},
  pages={1283 - 1286}
}
  • R. Force, M. Nahata
  • Published 1992
  • Chemistry, Medicine
  • Annals of Pharmacotherapy
  • OBJECTIVE: To discuss the potential of histamine H2-receptor antagonists (H2RAs) to cause malabsorption of vitamin B12 (cyanocobalamin). DATA SOURCES: Pertinent literature was identified via a MEDLINE search. Journals and references cited in published articles also were used as data sources. STUDY SELECTION: Studies evaluating the effect of H2RAs on vitamin B12 absorption were reviewed. DATA SYNTHESIS: H2RAs decrease acid secretion by the gastric parietal cells. Gastric acid and pepsin produced… CONTINUE READING
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