Effect of Helicobacter pylori infection and its eradication on cell proliferation, DNA status, and oncogene expression in patients with chronic gastritis.

@article{Nardone1999EffectOH,
  title={Effect of Helicobacter pylori infection and its eradication on cell proliferation, DNA status, and oncogene expression in patients with chronic gastritis.},
  author={Gerardo Nardone and Stefania Staibano and Alba Rocco and Ernesto Mezza and Francesco Paolo D'armiento and Luigi Insabato and Antonino Coppola and Gaetano Salvatore and Angela Lucariello and Natale Figura and Gaetano De Rosa and Gabriele Budillon},
  journal={Gut},
  year={1999},
  volume={44 6},
  pages={789-99}
}
BACKGROUND Helicobacter pylori, the main cause of chronic gastritis, is a class I gastric carcinogen. Chronic gastritis progresses to cancer through atrophy, metaplasia, and dysplasia. Precancerous phenotypic expression is generally associated with acquired genomic instability. AIM To evaluate the effect of H pylori infection and its eradication on gastric histology, cell proliferation, DNA status, and oncogene expression. METHODS/SUBJECTS Morphometric and immunohistochemical techniques… CONTINUE READING