Effect of Helicobacter pylori Infection on Ghrelin Expression in Human Gastric Mucosa

@article{Tatsuguchi2004EffectOH,
  title={Effect of Helicobacter pylori Infection on Ghrelin Expression in Human Gastric Mucosa},
  author={Atsushi Tatsuguchi and Kazumasa Miyake and Katya Gudis and Seiji Futagami and Taku Tsukui and Ken Wada and Teruyuki Kishida and Yuh Fukuda and Yuichi Sugisaki and Choitsu Sakamoto},
  journal={The American Journal of Gastroenterology},
  year={2004},
  volume={99},
  pages={2121-2127}
}
OBJECTIVES:One of the counter-effects of Helicobacter pylori eradication therapy is subsequent obesity. Ghrelin is a recently discovered growth hormone releasing peptide. This endogenous secretagogue increases appetite and facilitates fat storage. The majority of circulating ghrelin is produced in the gastric mucosa. Therefore, we aimed at investigating changes in ghrelin immunoreactivity in gastric mucosa tissues of patients infected with H. pylori.METHODS:Sixty-one patients with H. pylori… CONTINUE READING
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