Effect of Haemophilus influenzae endotoxin on the synthesis of IL-6, IL-8, TNF-alpha and expression of ICAM-1 in cultured human bronchial epithelial cells.

@article{Khair1994EffectOH,
  title={Effect of Haemophilus influenzae endotoxin on the synthesis of IL-6, IL-8, TNF-alpha and expression of ICAM-1 in cultured human bronchial epithelial cells.},
  author={Omer A Khair and Jagdish L Devalia and Mohamed M. Abdelaziz and Raymond J. Sapsford and H Tarraf and Rachel J. Davies},
  journal={The European respiratory journal},
  year={1994},
  volume={7 12},
  pages={2109-16}
}
Although studies of infective lung diseases have demonstrated that Haemophilus influenzae is a major pathogen, the mechanisms underlying pathogenesis by this organism are not clear. We have cultured human bronchial epithelial cells (HBEC) to confluency and have investigated the effect of H. influenzae endotoxin (HIE) on: 1) epithelial permeability, by movement of 14C-bovine serum albumin (14C-BSA) across HBEC and measurement of electrical resistance of HBEC; 2) release of interleukin-6 (IL-6… CONTINUE READING
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Effect of nitrogen dioxide on the synthesis of inflammatory cytokines expressed by human bronchial epithelial cells in vitro

  • JL Devalia, AM Campell, RJ Sapsford
  • Am J Respir Cell Mol Biol
  • 1993
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