Effect of Gum Arabic on Liver Function And Antioxidant Enzymes of Sprague-Dawley Rats

  title={Effect of Gum Arabic on Liver Function And Antioxidant Enzymes of Sprague-Dawley Rats},
  author={Mohammed Babiker and Tarig Abbas and Mohammed Elimam Ahamed Mohammed},
  journal={IOSR Journal of Pharmacy and Biological Sciences},
The aim of this study was to investigate the effect of twelve weeks Gum Arabic dose on the liver functions and some antioxidant enzymes activity of 10 Sprague-Dawley rats. Methods: 10 normal Sprague-Dawley rats were fed one liter 10% of gum Arabic solution daily for 12 weeks. As a control group another 10 rats were not fed with gum Arabic. On week twelve, blood samples were collected from each rat and all of them were killed and the liver was obtained. Some of the liver was homogenized and the… 

Therapeutic Effect of Gum Arabic on some Biochemical Parameters in Nephrotoxic Albino rats

The present study concluded that the induced nephrotoxicity group treated with Gum Arabic showed improvement in some biochemical and hematological parameters associated mainly with neph rotoxicity.

Study the Protective Role of Arabic Gum Extract on Some Physiological and Histological Criteria for Liver of Male Rabbit Treated with Atrazine

The study involved fifteen health adult male rabbit white (Lepus arcticus), weight ranged (1480-1550) kg. and age between 6 to 8 month, divided to three groups the first group treated 10 ml of

Hepato-toxic risk of gum arabic during adenine-induced renal toxicity prevention

It is proven that GA supplementation produces harmful effects on liver as it elevates ALT and AST levels and it would be more benefit for such patients to use a hepato-protective supplement in addition to GA supplement for better outcomes.

Effects of Probiotics and Prebiotics Dietary Supplementations on Some Parameters of Diabetic Rats

The obtained results suggested that AG is highly recommended with to be used as dietary medication especially at the level 5% for diabetic and hyperlipidemia patients, however, further human studies are needed.

Clinical effects of Gum Arabic (Acacia): A Mini Review

Gum Arabic (GA) is a natural gummy exudate gained from the trees of Acacia species (Acacia senegal and Acacia seyal), Family: Fabaceae. GA is considered as a dietary fiber with a high percentage of



Does Gum Arabic Have an Antioxidant Action in Rat Kidney?

  • B. Ali
  • Biology
    Renal failure
  • 2004
It seems highly unlikely that gum Arabic has a palliative effect on renal failure through an anti‐oxidant mechanism.

Protective role and antioxidant activity of arabic gum againsttrichloroacetate-induced toxicity in liver of male rats

It is demonstrated that AG supplementation for 2 months in TCA induced toxicity in rats benefited hepatic antioxidant status and improved liver injury and damage in male albino rats exposed to TCA.

Gum Arabic extracts protect against hepatic oxidative stress in alloxan induced diabetes in rats.

Amelioration of indomethacin systemic toxicity by gum arabic administration in adult albino rats

Administration of gum arabic with high dose of indomethacin induced significant improvement of its systemic toxicity manifestations in the rats, leading to statistical significant abnormalities of liver and renal function tests, complete blood picture and coagulation profile associated with significant disturbance of antioxidant mechanism.

The Effect Of Gum Arabic Supplements On Sodium Valproate-Induced Hepatotoxicity In Rats

Although treatment with valproate in combination with Gum Arabic resulted in a significant rise in ALP level throughout the period of treatment; the rise was significantly lower than that recorded for group (A) at the respective times, and combination therapy restored the decrease that occurred.

Biochemical effect of chronically administered suspending agents on mitochondrial metabolism and hepatic mixed function oxidases in rat, mice, and hamster.

  • E. BachmannG. Zbinden
  • Biology, Chemistry
    Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement
  • 1978
It is concluded that several of the conventionally used suspending agents cannot be considered inert, and are capable of inducing significant enzyme changes in various organs of experimental animals.

Effect of sucrose acetate isobutyrate (SAIB) ingestion on the hepatobiliary function of normal human male and female volunteers.

  • M. ChiangK. GrayC. Chappel
  • Medicine
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
  • 1998

Effect of gum arabic on quality and antioxidant properties of papaya fruit during cold storage

Coating of papaya fruit (Carica papaya L. cv Hongkong) with gum arabic (GA) has been found to enhance their shelf-life and postharvest quality. The objective of this study was to determine the effect