Effect of Grape Seed Extract and Quercetin on Cardiovascular and Endothelial Parameters in High-Risk Subjects

@article{Clifton2004EffectOG,
  title={Effect of Grape Seed Extract and Quercetin on Cardiovascular
and Endothelial Parameters in High-Risk Subjects},
  author={Peter M Clifton},
  journal={Journal of Biomedicine and Biotechnology},
  year={2004},
  volume={2004},
  pages={272 - 278}
}
Grape seed extract (GSE) has in vitro antioxidant activity but whether or not it works in vivo is not clear. In a fully randomised, crossover trial with 4-week treatment periods on 36 men and women with above-average vascular risk, we aimed to demonstrate that 2 g/day of GSE (1 g of polyphenols) alone, or with 1 g/day of added quercetin in yoghurt, favourably alters vascular function, endothelial function, and degree of oxidative damage in comparison to a control yoghurt. GSE alone improved… CONTINUE READING
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