Effect of GABA A receptor activation on UT-coupled signaling pathways in rat cortical astrocytes.

@article{Desrues2008EffectOG,
  title={Effect of GABA A receptor activation on UT-coupled signaling pathways in rat cortical astrocytes.},
  author={Laurence Desrues and Thomas Lefebvre and Micka{\"e}l Diallo and Pierrick Gandolfo and J{\'e}r{\^o}me Leprince and David Chatenet and Hubert Vaudry and M. Tonon and H{\'e}l{\`e}ne Castel},
  journal={Peptides},
  year={2008},
  volume={29 5},
  pages={727-34}
}
Cultured rat cortical astrocytes express two types of urotensin II (UII) binding sites: a high affinity site corresponding to the UT (GPR14) receptor and a low affinity site that has not been fully characterized. Activation of the high affinity site in astroglial cells stimulates polyphosphoinositide (PIP) turnover and provokes an increase in intracellular… CONTINUE READING