Effect of Food Restriction on Life Span and Immune Functions in Long-Lived Fischer-344 × Brown Norway F1 Rats

Abstract

Life-long food restriction is known to slow aging and reduce the rate of occurrence of age-associated disease processes, but the mechanism by which this is accomplished is unknown. In this study we have examined the effect of food restriction on the proliferative response of spleen cells to mitogens and lymphokine production in 6-, 18-, and 30-month-old AL… (More)
DOI: 10.1023/A:1027344730553

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