Effect of Fluticasone Furoate and Vilanterol on Exacerbations of Chronic Obstructive Pulmonary Disease in Patients with Moderate Airflow Obstruction.

@article{Martinez2017EffectOF,
  title={Effect of Fluticasone Furoate and Vilanterol on Exacerbations of Chronic Obstructive Pulmonary Disease in Patients with Moderate Airflow Obstruction.},
  author={Fernando J Martinez and J\orgen Vestbo and Julie Anne Anderson and Robert D. Brook and Bartolome R Celli and Nicholas J. Cowans and Courtney C Crim and Mark Thomas Dransfield and Sally Kilbride and Julie Carol Yates and David E. Newby and Dennis E. Niewoehner and Peter M. A. Calverley},
  journal={American journal of respiratory and critical care medicine},
  year={2017},
  volume={195 7},
  pages={
          881-888
        }
}
RATIONALE Inhaled corticosteroids have been shown to decrease exacerbations in patients with moderate to severe chronic obstructive pulmonary disease (COPD). Their effects in patients with milder airflow obstruction remain unclear. OBJECTIVES This was an analysis of exacerbations in the SUMMIT (Study to Understand Mortality and Morbidity) study. METHODS In a double-blind, randomized controlled trial, once-daily inhaled placebo, fluticasone furoate (FF; 100 μg), vilanterol (VI; 25 μg), or… CONTINUE READING
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