Effect of First-Line Treatment on Myeloid-Derived Suppressor Cells' Subpopulations in the Peripheral Blood of Patients with Non-Small Cell Lung Cancer.

@article{Koinis2016EffectOF,
  title={Effect of First-Line Treatment on Myeloid-Derived Suppressor Cells' Subpopulations in the Peripheral Blood of Patients with Non-Small Cell Lung Cancer.},
  author={Filippos Koinis and Eleni Kyriaki Vetsika and Despoina Aggouraki and Eleftheria Skalidaki and Anna Koutoulaki and Marianthi Gkioulmpasani and Vassilis Georgoulias and Athanasios A Kotsakis},
  journal={Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer},
  year={2016},
  volume={11 8},
  pages={1263-1272}
}
INTRODUCTION Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immature cells of myeloid origin whose expression is induced by, among others things, vascular endothelial growth factor. We have previously identified two monocytic and one granulocytic MDSC subpopulations associated with the clinical outcome in patients with non-small cell lung cancer (NSCLC). The aim of the present study was to evaluate the effect of chemotherapy on these MDSC subpopulations. METHODS… CONTINUE READING
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