Effect of Fiber Length on Carbon Nanotube-Induced Fibrogenesis

  title={Effect of Fiber Length on Carbon Nanotube-Induced Fibrogenesis},
  author={Amruta Manke and Sudjit Luanpitpong and Chenbo Dong and Liying Wang and Xiaoqing He and Lori A. Battelli and Raymond C Derk and Todd A Stueckle and Dale W. Porter and Tina Sager and Honglei Gou and Cerasela Zoica Dinu and Nianqiang Wu and Robert R. Mercer and Yon Rojanasakul},
  booktitle={International journal of molecular sciences},
Given their extremely small size and light weight, carbon nanotubes (CNTs) can be readily inhaled by human lungs resulting in increased rates of pulmonary disorders, particularly fibrosis. Although the fibrogenic potential of CNTs is well established, there is a lack of consensus regarding the contribution of physicochemical attributes of CNTs on the underlying fibrotic outcome. We designed an experimentally validated in vitro fibroblast culture model aimed at investigating the effect of fiber… CONTINUE READING
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