Effect of Erythritol and Xylitol on Dental Caries Prevention in Children

@article{Honkala2014EffectOE,
  title={Effect of Erythritol and Xylitol on Dental Caries Prevention in Children},
  author={Sisko Honkala and Riina Runnel and Mare Saag and Jana Olak and Rita N{\~o}mmela and Silvia Russak and P. -L. M{\"a}kinen and Tero Vahlberg and Gwen Falony and Kauko K M{\"a}kinen and Eino J Honkala},
  journal={Caries Research},
  year={2014},
  volume={48},
  pages={482 - 490}
}
Objective: The aim of this study was to test the efficacy of long-term, daily intake of erythritol and xylitol candy, compared with sorbitol candy, on the development of enamel and dentin caries lesions. Methods: The study was a double-blind randomized controlled prospective clinical trial. Altogether 485 primary school children, first- and second-graders at baseline, from southeastern Estonia participated in this 3-year intervention. Each child consumed four erythritol, xylitol or sorbitol… Expand

Paper Mentions

Interventional Clinical Trial
This study aims at demonstrating the effect of erythritol and xylitol lozenges on preventing the new caries lesions and the possible remineralization effect of both polyols on incipient… Expand
ConditionsDental Caries
InterventionDietary Supplement
Long-Term Effect of Erythritol on Dental Caries Development during Childhood: A Posttreatment Survival Analysis
TLDR
A caries-preventive effect of 3-year erythritol consumption as compared to sorbitol was established in children with mixed dentition and the effect persisted up to 3 years after the end of the intervention. Expand
Effect of three-year consumption of erythritol, xylitol and sorbitol candies on various plaque and salivary caries-related variables.
TLDR
Three-year consumption of erythritol-containing candies by initially 7- to 8-year old children was associated with reduced plaque growth, lower levels of plaque acetic acid and propionic acid, and reduced oral counts of mutans streptococci compared with the consumption of xylitol or sorbitol candies. Expand
Effectiveness of Xylitol in Reducing Dental Caries in Children.
TLDR
The present systematic review examining the effectiveness of xylitol on caries incidence in children showed a small effect size in randomized controlled trials and a very low quality of evidence that makes preventive action ofxylitol uncertain. Expand
Evaluation of xylitol use and bitewing radiographs among school-aged children in a low-caries level population
TLDR
The conducted systematic review revealed that caries-preventive effect of xylitol was well shown in highcaries level populations, and bothxylitol and erythritol decreased the adherence of polysaccharide-producing oral streptococci. Expand
Erythritol Is More Effective Than Xylitol and Sorbitol in Managing Oral Health Endpoints
TLDR
Evidence is provided demonstrating better efficacy of erythritol compared to sorbitol and xylitol to maintain and improve oral health. Expand
Clinical Evidence for Polyol Efficacy
TLDR
One new completed trial confirmed that children of mothers who used xylitol lozenges after delivery had less dental caries than a comparison group and a similar study confirmed that the use ofxylitol gum by the mother either prevented or postponed MS transmission to the offspring. Expand
Comment on the Paper Entitled ‘Effect of Erythritol and Xylitol on Dental Caries Prevention in Children'
TLDR
Exfoliation of (carious) primary molars and replacement by permanent premolars (with no cariogenic challenge time) explains the decline in caries prevalence in adults. Expand
The Biocompatibility of a New Erythritol-and Xyltol-Containing Fluoride Toothpaste
TLDR
AirFlow-AF showed high biocompatibility with different cell types and the half lethal concentration (LC50) as well as the proliferation behavior on gingival, periodontal ligament, and mouse fibroblast cells were tested. Expand
Xylitol-containing products for preventing dental caries in children and adults.
TLDR
The main finding of the review was that, over 2.5 to 3 years of use, a fluoride toothpaste containing 10% xylitol may reduce caries by 13% when compared to a fluoride-only toothpaste, and the remaining evidence on children, from small single studies with risk of bias issues and great uncertainty associated with the effect estimates, was insufficient to determine a benefit fromxylitol products. Expand
Caries Incidence in a Healthy Young Adult Population in Relation to Diet
TLDR
In this healthy young adult population, caries was found in 97.8% of the subjects, mostly initial enamel caries (ICDAS 1 to 2) in the occlusal surface of molars, and was related with dietary factors. Expand
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The results suggest that not only xylitol chewing gum but alsoxylitol candies are effective in caries prevention, and that a school-based delivery system seems to offer a practical way to distribute and control the use of the xylitor products. Expand
Effect of three-year consumption of erythritol, xylitol and sorbitol candies on various plaque and salivary caries-related variables.
TLDR
Three-year consumption of erythritol-containing candies by initially 7- to 8-year old children was associated with reduced plaque growth, lower levels of plaque acetic acid and propionic acid, and reduced oral counts of mutans streptococci compared with the consumption of xylitol or sorbitol candies. Expand
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TLDR
Erythritol and xylitol may exert similar effects on some risk factors of dental caries, although the biochemical mechanism of the effects may differ. Expand
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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