Effect of Epithalon on the Incidence of Chromosome Aberrations in Senescence-Accelerated Mice

@article{Rosenfeld2002EffectOE,
  title={Effect of Epithalon on the Incidence of Chromosome Aberrations in Senescence-Accelerated Mice},
  author={Svetlana V. Rosenfeld and E. F. Togo and Vladimir Mikheev and Irina G. Popovich and M. A. Zabezhinskii and Vladimir Kh. Khavinson and Vladimir N. Anisimov},
  journal={Bulletin of Experimental Biology and Medicine},
  year={2002},
  volume={133},
  pages={274-276}
}
The incidence of chromosome aberrations in bone marrow cells of 12-month-old SAMP-1 female mice characterized by accelerated aging was 1.8 times higher than in wild-type SAMR-1 females and 2.2 times higher than in SHR females of the same age. Treatment with Epithalon (Ala-Glu-Asp-Gly) starting from the age of 2 months decreased the incidence of chromosome… CONTINUE READING