Effect of Epinephrine on Adrenal Ascorbic Acid Following Premedication With Lysergic Acid Diethylamides or 5-Hydroxyindolalkylamines

@article{Costa1958EffectOE,
  title={Effect of Epinephrine on Adrenal Ascorbic Acid Following Premedication With Lysergic Acid Diethylamides or 5-Hydroxyindolalkylamines},
  author={E. Costa and G. Zetler},
  journal={Proceedings of the Society for Experimental Biology and Medicine},
  year={1958},
  volume={98},
  pages={249 - 252}
}
  • E. Costa, G. Zetler
  • Published 1 June 1958
  • Chemistry, Medicine
  • Proceedings of the Society for Experimental Biology and Medicine
Summary 10 γ/kg i.p. of LSD potentiate the adrenal ascorbic acid depletion caused in rats by 25 γ/kg i.p. of epinephrine, 40 γ/kg i.p. of BOL are ineffective in this respect. 30 γ/kg i.p. of both serotonin and bufotenin potentiate the effects of epinephrine (25 γ/kg i.p.). The threshold doses of bufotenin and serotonin enhancing the epinephrine induced contractions of cat's nictitating membrane were 4.82 γ/kg i.v. and 88.01 γ/kg i.v. 
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