Effect of E-cadherin Expression on Hormone Production in Rat Anterior Pituitary Lactotrophs In Vitro

@inproceedings{Kusumoto2010EffectOE,
  title={Effect of E-cadherin Expression on Hormone Production in Rat Anterior Pituitary Lactotrophs In Vitro},
  author={Kenji Kusumoto and Motoshi Kikuchi and Ken Fujiwara and Kotaro Horiguchi and Tom Kouki and Kotaro Kawanishi and Takashi Yashiro},
  booktitle={Acta histochemica et cytochemica},
  year={2010}
}
Cadherins are a family of transmembrane glycoproteins that mediate cell-to-cell adhesion. A change in cadherin type in cells, i.e., cadherin switching, induces changes in the character of the cell. Recent studies of the developing rat adenohypophysis found that primordial cells co-expressed E- and N-cadherins, but that hormone-producing cells lost E-cadherin and ultimately possessed only N-cadherin. In the present study, we examined the roles of cadherin switching in cytogenesis of anterior… CONTINUE READING
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