Effect of Dopamine Agonists on Lactotroph Adenomas of the Human Pituitary.

Abstract

Dopamine (DA) agonists cause reduction of blood prolactin level and tumor shrinkage in most patients with lactotroph adenoma. Our aim was to investigate the cellular mechanism of tumor shrinkage by determining mitotic, MIB-1, p27, and apoptotic indices, as well as microvessel density (MVD), surface microvessel density (SMD). ploidy, and other nuclear… (More)

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Cite this paper

@article{Stefaneanu2000EffectOD, title={Effect of Dopamine Agonists on Lactotroph Adenomas of the Human Pituitary.}, author={Lucia Stefaneanu and Kalman T. Kovacs and Bernd Walter Scheithauer and George Kontogeorgos and Darren L. Riehle and Thomas J. Sebo and David W. Murray and Sergio Vidal and Ami Tran and Michael Buchfelder and Rudolf Fahlbusch}, journal={Endocrine pathology}, year={2000}, volume={11 4}, pages={341-352} }