Effect of Diclofenac with B Vitamins on the Treatment of Acute Pain Originated by Lower-Limb Fracture and Surgery

@article{PonceMonter2012EffectOD,
  title={Effect of Diclofenac with B Vitamins on the Treatment of Acute Pain Originated by Lower-Limb Fracture and Surgery},
  author={H{\'e}ctor A. Ponce-Monter and Mario I. Ortiz and Alexis F. Garza-Hern{\'a}ndez and Ra{\'u}l Monroy-Maya and Marisela Soto-R{\'i}os and Lourdes Cristina Carrillo-Alarc{\'o}n and Gerardo Reyes‐Garc{\'i}a and Eduardo Fern{\'a}ndez-Mart{\'i}nez},
  journal={Pain Research and Treatment},
  year={2012},
  volume={2012}
}
The aim of this study was to compare the efficacy of diclofenac, for the treatment of acute pain originated by lower-limb fracture and surgery, with that of diclofenac plus B vitamins. This was a single-center, prospective, randomized, and double-blinded clinical trial. Patients with lower-limb closed fractures rated their pain on a 10 cm visual analog scale (VAS). Patients were then randomized to receive diclofenac or diclofenac plus B vitamins (thiamine, pyridoxine, and cyanocobalamin… 

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