Effect of Delayed Peripheral Nerve Repair on Nerve Regeneration, Schwann Cell Function and Target Muscle Recovery

@inproceedings{Jonsson2013EffectOD,
  title={Effect of Delayed Peripheral Nerve Repair on Nerve Regeneration, Schwann Cell Function and Target Muscle Recovery},
  author={Samuel Jonsson and Rebecca Wiberg and Aleksandra M. McGrath and Lev N. Novikov and Mikael Wiberg and Liudmila N. Novikova and Paul J Kingham},
  booktitle={PloS one},
  year={2013}
}
Despite advances in surgical techniques for peripheral nerve repair, functional restitution remains incomplete. The timing of surgery is one factor influencing the extent of recovery but it is not yet clearly defined how long a delay may be tolerated before repair becomes futile. In this study, rats underwent sciatic nerve transection before immediate (0) or 1, 3, or 6 months delayed repair with a nerve graft. Regeneration of spinal motoneurons, 13 weeks after nerve repair, was assessed using… CONTINUE READING
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