Effect of DA‐8031, a novel oral compound for premature ejaculation, on male rat sexual behavior

@article{Kang2014EffectOD,
  title={Effect of DA‐8031, a novel oral compound for premature ejaculation, on male rat sexual behavior},
  author={K. K. Kang and J. Sung and S. H. Kim and S. Lee},
  journal={International Journal of Urology},
  year={2014},
  volume={21}
}
  • K. K. Kang, J. Sung, +1 author S. Lee
  • Published 2014
  • Medicine
  • International Journal of Urology
    • DA‐8031 is a potent and selective serotonin transporter inhibitor developed for the treatment of premature ejaculation. The aim of the present study was to investigate the effects of DA‐8031 on male sexual behavior in a rat model. 
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    References

    SHOWING 1-10 OF 31 REFERENCES
    A comparison of the effects of different serotonin reuptake blockers on sexual behaviour of the male rat
    • 84
    Delay of ejaculation induced by SB-277011, a selective dopamine D3 receptor antagonist, in the rat.
    • 45
    The selective serotonin re-uptake inhibitors fluvoxamine and paroxetine differ in sexual inhibitory effects after chronic treatment
    • 73
    The effects of oral administration of d-modafinil on male rat ejaculatory behavior.
    • 20
    Ejaculatory responses are inhibited by a new chemical entity, DA-8031, in preclinical rodent models of ejaculation.
    • 17
    Effect of dexmedetomidine on ejaculatory behavior and sexual motivation in intact male rats
    • 8
    Animal models of ejaculatory behavior.
    • 48
    Effects of chronic selective serotonin reuptake inhibitors on 8-OH-DPAT-induced facilitation of ejaculation in rats: comparison of fluvoxamine and paroxetine
    • 59
    Candidate molecule for premature ejaculation, DA-8031: in vivo and in vitro characterization of DA-8031.
    • 17
    Utility of selective serotonin reuptake inhibitors in premature ejaculation.
    • 63