Effect of Combination Therapy of Methotrexate with Vitamin A in Patients with Low Risk GTN (Gestational Trophoblastic Neoplasia)

  title={Effect of Combination Therapy of Methotrexate with Vitamin A in Patients with Low Risk GTN (Gestational Trophoblastic Neoplasia)},
  author={Sedigheh Ghasemian and Z Karkhaneh Yousefi and Marjaneh Farazestanian and Leila Mousavi Seresht and Mohsen Foroughipour and Saeid Akhlaghi},
  journal={Iranian Journal of Pharmaceutical Research : IJPR},
  pages={38 - 42}
Methotrexate as a single agent chemotherapy in most women with low risk gestational trophoblastic neoplasia (GTN) has been associated with high treatment rate. Combination of methotrexate with Vitamin A due to reduced number of chemotherapy regime courses is one of the treatment options for patients with low-risk GTN. Therefore, this study was performed with aim to determine the efficacy of combination therapy of Methotrexate with Vitamin A in low risk GTN treatment. This randomized clinical… 

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