Effect of Cocaine on Dopamine Transporter Receptors Depends on Routes of Chronic Cocaine Administration

@article{Hitri1996EffectOC,
  title={Effect of Cocaine on Dopamine Transporter Receptors Depends on Routes of Chronic Cocaine Administration},
  author={Ana Hitri and Karley Y. Little and Everett H. Ellinwood},
  journal={Neuropsychopharmacology},
  year={1996},
  volume={14},
  pages={205-210}
}
Investigation of residual behavioral states produced by withdrawal from different routes of cocaine administration indicates that depending on the mode of intake, chronic cocaine produces either tolerance or sensitization to subsequent challenge doses of cocaine. We studied the effect of routes of cocaine administration on the dopamine transporter receptors (DATR), the presumed neuronal mediator of cocaine reward, using the diphenyl substituted piperazine derivative, [3H]GBR 12935 and the… CONTINUE READING

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Classic Studies on the Interaction of Cocaine and the Dopamine Transporter.

Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology • 2015

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