Effect of Carcinogens on Chicken Atherosclerosis1


Weekly i.m. injections of the polycyclic hydrocarbon car cinogens, 7,12-dimethylbenz(a,h)anthracene (DMBA; 25 mg/ kg/injection) and benzo(a)pyrene (50 mg/kg/injection) were given for a period of up to 22 weeks to chickens (SC strain) beginning at age 4 weeks. Atherosclerotic lesions of the abdominal aorta occurred more frequently and were larger in the… (More)


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