Effect of Carboxamide Derivative IS-741 on Rat Spontaneous Chronic Pancreatitis

Abstract

This study aimed to analyze the therapeutic effects of the carboxamide derivative IS-741 on spontaneous chronic pancreatitis (CP) in the WBN/Kob rat. Four-week-old male WBN/Kob rats were fed with MB-3, and IS-741 (0.012% in MB-3) was orally administered for 12 weeks. Cytokine-induced neutrophil chemoattractant (CINC), interleukin (IL) -6, pancreatitis… (More)
DOI: 10.1023/A:1013232024148

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