Effect of Cannabidiol on Drop Seizures in the Lennox-Gastaut Syndrome.

@article{Devinsky2018EffectOC,
  title={Effect of Cannabidiol on Drop Seizures in the Lennox-Gastaut Syndrome.},
  author={Orrin Devinsky and Anup D. Patel and J. Helen Cross and Vicente Villanueva and Elaine C. Wirrell and Michael D. Privitera and Sam Greenwood and Claire Roberts and Daniel Checketts and Kevan E Vanlandingham and Sameer M Zuberi},
  journal={The New England journal of medicine},
  year={2018},
  volume={378 20},
  pages={
          1888-1897
        }
}
BACKGROUND Cannabidiol has been used for treatment-resistant seizures in patients with severe early-onset epilepsy. We investigated the efficacy and safety of cannabidiol added to a regimen of conventional antiepileptic medication to treat drop seizures in patients with the Lennox-Gastaut syndrome, a severe developmental epileptic encephalopathy. METHODS In this double-blind, placebo-controlled trial conducted at 30 clinical centers, we randomly assigned patients with the Lennox-Gastaut… CONTINUE READING
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