Effect of Cannabidiol on Drop Seizures in the Lennox–Gastaut Syndrome

@article{Devinsky2018EffectOC,
  title={Effect of Cannabidiol on Drop Seizures in the Lennox–Gastaut Syndrome},
  author={O. Devinsky and A. Patel and Helen J. Cross and V. Villanueva and E. Wirrell and M. Privitera and S. Greenwood and C. Roberts and Daniel Checketts and K. Vanlandingham and S. Zuberi},
  journal={The New England Journal of Medicine},
  year={2018},
  volume={378},
  pages={1888–1897}
}
  • O. Devinsky, A. Patel, +8 authors S. Zuberi
  • Published 2018
  • Medicine
  • The New England Journal of Medicine
  • Background Cannabidiol has been used for treatment‐resistant seizures in patients with severe early‐onset epilepsy. [...] Key Method Methods In this double‐blind, placebo‐controlled trial conducted at 30 clinical centers, we randomly assigned patients with the Lennox–Gastaut syndrome (age range, 2 to 55 years) who had had two or more drop seizures per week during a 28‐day baseline period to receive cannabidiol oral solution at a dose of either 20 mg per kilogram of body weight (20‐mg cannabidiol group) or 10 mg…Expand Abstract

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